Wednesday, August 4, 2010

Mean Corpuscular Hemoglobin (MCH)

Mean Corpuscular Hemoglobin (MCH)

Introduction

MCH is calculated as Hb divided by total RBC count.

Normal range

            Adults – 27-31Pg
            New born – 33- 39Pg

Indications

Limited value in differential diagnosis of anemias; Used for instrument calibration.

Increased in

Macrocytic anemia, infants and newborns, marked leukocytosis( > 50,000/cu.mm),cold agglutinins, in vivo hemolysis, monoclonal proteins in blood, high heparin concentration, lipemia.

Decreased in

Microcytic and normocytic anemias.

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