Causes of Neutrophilia (Increased Neutrophil) (Absolute count > 8000/ cu.mm.)

Causes of Neutrophilia (Absolute count > 8000/ cu.mm.)  

·        Acute infections:

·        Localized (e.g. Pneumonia, meningitis, tonsillitis).

·        Generalized (e.g. acute rheumatic fever, septicemia, cholera).

·        Inflammation (e.g. vasculitis).

·        Intoxications: metabolic (e.g. acidosis, uremia, acute gout); Poisonings (e.g. mercury, epinephrine, black widow spider bite).

·        Acute hemorrhage or hemolysis of red blood cells.

·        Tissue necrosis (e.g. acute myocardial infarction [AMI], burns, gangrene).

·        Physiological (e.g. exercise, Stress, obstetric labor, menstrution).

Differential leukocyte Count (DLC)

Differential leukocyte Count (DLC)

Normal Range
Granulocytes	Percentage	Agranulocytes	Percentage
Neutrophils	54-62 %	Lymphocytes	20- 40 %
Eosinophils	1-4 %	Monocytes	3-7 %
Basophils	< 1 %

Indications

 Support diagnosis of various infections and inflammation; 
diagnosis of myeloproliferative disorders;
neutrophil and band counts may be useful in acute appendicitis and 
neonatal sepsis with moderate sensitivity and specificity

TLC Decreased

Leukopenia in

Some bacterial infections (e.g. typhoid), 
viral or protozoal infection, 
bone marrow depression and 
starvation and 
physiological at night.