Wednesday, October 13, 2010

Serum Globin

1.      Serum Globin


Globulins are produced by variety of tissue including liver. Serum globulins include alpha and beta globulins as well as serum immunoglobulins.

Normal range

   Adults: 1.9 – 3.5 gm/Dl

   Fetal: 0.4 – 3.7gm/dL



To evaluate chronic liver diseases and cirrhosis (increases to varying degrees).


Increased in

Chronic liver diseases and cirrhosis; increase may be present in non- hepatic disorders or may reflect increased stimulation of peripheral reticuloendothelial compartment due to shunting of antigens past the liver and impaired clearance by kuffer cells.  

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