Serum Globin

1.      Serum Globin

Introduction

Globulins are produced by variety of tissue including liver. Serum globulins include alpha and beta globulins as well as serum immunoglobulins.

Normal range
Adults: 1.9 – 3.5 gm/Dl	Fetal: 0.4 – 3.7gm/dL

 

 Indications

To evaluate chronic liver diseases and cirrhosis (increases to varying degrees).

 

Increased in

Chronic liver diseases and cirrhosis; increase may be present in non- hepatic disorders or may reflect increased stimulation of peripheral reticuloendothelial compartment due to shunting of antigens past the liver and impaired clearance by kuffer cells.