Basophilia (50/cumm or > 1%)

Basophilia (50/cumm or > 1%)

May be first sign of blast crisis or accelerated phase of chronic myelocytic leukemia (CML).

Persistent basophilia may indicate unsuspected myeloproliferative disease.

Causes

Chronic myelogenous leukemia, basophilic leukemia, polycythemia, myeloid metaplasia, Hodgkin's disease, chronic sinusitis and hemolytic anemia.

Causes of lymphocytopenia (Decreased Lymphocytes) (< 1500 in adults, < 3000 in children)

Causes of lymphocytopenia (< 1500 in adults, < 3000 in children)

Increased destruction (chemotherapy or radiation treatment, corticosteroids), 

increased loss via Gl tract (thoracic duct drainage obstruction to intestinal lymphatic duct drainage), 

congestive heart failure, 

decreased production (aplastic anemia, malignancy, AlDS).

Causes of lymphocytosis (Increased Lymphocytes) (> 4000/cumm in adults, > 7200/cumm adolescents, > 9000/cumm in children and infants)

Causes of lymphocytosis (> 4000/cumm in adults, > 7200/cumm adolescents, > 9000/cumm in children and infants)

Infection (Pertusis, infectious, lymphocytosis, infectious hepatitis, cytomegalovirus (CMV) infections, mumps, rubella, varicella, toxoplasmosis, chronic tuberculosis), 

Others like 

thyrotoxicosis,

Addison's disease, 

neutropenia with relative lymphocytosis, 

lymphatic leukemia, 

Crohn's disease, 

ulcerative colitis and 

infancy (normal count 40- 60 %) called relative lymphocytosis.