Saturday, July 31, 2010

Mean Corpuscular Volume (MCV)

Mean Corpuscular Volume (MCV)

Introduction
MCV is calculated as hematocrit (Hct) divided by RBC count with manual methods measured directly by automated instruments.
 
Normal range
Adults – 78-100Fl
Neonates- 102-115Fl.

Indications
Classification and differential diagnosis of anemia; useful screening test for occult alcoholism

Increased in (MCV > 95fL, Often > 110Fl)
All macrocytic anemias (megaloblastic anemias, Vit. B12’ folate deficiency, sprue, macrocytic anemia of pregnancy, megaloblastic anemia due to alcoholism, liver disease and hypothyroidism), infants and newborns.
 
Decrease in (MCV < 80FL)
Microcytic anemias
Usually hypo chromic (e.g. iron deficiency, pyridoxine – responsive thalassemia,   lead poisoning), chronic disease, abnormal HbC and HbE.

Total Erythrocyte Count (RBC Count)

Total Erythrocyte Count (RBC Count)

Normal range (x 106cumm)

       Adult Males

      Adult Females

           Newborn

          4.7- 6.0

          4.2 –5.4

          4.1-6.7

Hemoglobin Decreased In

Hemoglobin Decreased in

All pathological causes of anemia; 
physiological in infants after 3 months of life (as infant is totally on milk feed, devoid of iron).

Friday, July 30, 2010

Hemoglobin Increased In

Hemoglobin Increased in

Chronic hypoxia of bone marrow due to exercise or any cardio respiratory disorder; 
polycythemia vera; 
physiological (normal) in newborn;
adults at high altitude.

Hemoglobin (Hb) Nomal Values

   Hemoglobin (Hb)

Normal range (g/dl)

   Males

   Females

   Newborn

  3Months

  1Years

 13.5-18

   12.5-16

    15-24

     10.5

    12.5

Thursday, July 29, 2010

Complete Blood Count CBC

Tests included in CBC, Complete Blood Count

Hb,
TLC,
DLC,
RBC count
ESR
MCV
MCHC
MCH
Platelet Count
PCV
Peripheral Smear